New Appetite Control Mechanism Discovered in Brain
Original Article: http://neurosciencenews.com/appetite-control-mechanism-6536/ This study identified a new molecule involved in appetite. This molecule, known as NPGL increases one’s appetite during a period of fasting and decreases it while eating. It is thought that this molecule aims to keep body mass at a constant and to maintain homeostasis. NPGL plays a very important role in what scientists believed to be the thoroughly understood process of appetite and hunger. This substance was first discovered in chickens but now is known to be present in all vertebrates. The research of this study aimed to explore NPGL in mice. One group of mice were fed a very low calorie diet for 24 hours. Another group was given a very high fat diet over the span of five weeks. The last group was fed on a very high fat diet as well but for 13 weeks. The mice that were on the low calorie diet had a drastic increase in the NPGL expression while the other group of mice on the five week high fat di...